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Sivasakthi, R.
- Anti-Inflammatory Activity Screening of Methanolic Extract of Bryophyllum pinnatum Root
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1 Department of Pharmacology, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore – 641402., IN
2 Department of Pharmacy Practice, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore – 641402., IN
3 Department of Pharmacognosy, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore – 641402., IN
1 Department of Pharmacology, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore – 641402., IN
2 Department of Pharmacy Practice, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore – 641402., IN
3 Department of Pharmacognosy, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore – 641402., IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 14, No 1 (2022), Pagination: 1-3Abstract
An inflammatory response appears after activation of immune response. Inflammation is a response to remove the primary cause of cell injury. Dead cells, damage tissue sand initiate the repair process. Inflammation may be of two types acute and chronic. Medicinal plants has a potential source of therapeutic aid has a attended a significant role in all over the world for both human and animals not only in the disease condition but also a potential for maintaining a proper health. The plant Bryophyllum pinnatum species (roots) are evaluated for anti-inflammatory activity. Aim: Anti-inflammatory activity of Bryophyllum pinnatum was evaluated using Carrageenan induced paw oedema, Histamine induced paw oedema and Egg white induced paw oedema. Materials and Methods: To prepare methanolic extracts of Bryophyllum pinnatum roots and investigate the anti-inflammatory activity by Carrageenan induced paw oedema, Histamine induced paw oedema and Egg white induced paw oedema. Result: The result obtained indicates that the extract found to have significant (p<0.0001) anti-inflammatory activity in rats. The extract at the test doses 200mg/kg reduced the oedema induced by carrageenan by 41.26% at 3 h, whereas the standard drug showed 47.35% of inhibition ass compared to the control group. Conclusion: The methanolic extract of Bryophyllum pinnatum are safe upto 500mg/kg for continues administration and it can be used as anti inflammatory agent without any harmful effectsKeywords
Inflammation, Oedema, Therapeutic aid, anti-inflammatory activity, Histamine.References
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- Latif A, Ashiq K, Ashiq S, Ali E, Anwer I, Qamar S. Phytochemical analysis and in vitro investigation of antiinflammatory and xanthine oxidase inhibition potential of root extracts of Bryophyllum pinnatum. J Anim Plant Sci. 2020 Feb 1;30(1):219-28.
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- A Study on Prevalence and Risk Factors of Anaemia among patients at Tertiary Care Hospital
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Authors
Affiliations
1 Department of Pharmacy Practice, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore, Tamil Nadu – 641402, IN
2 General Medicine, KG Hospital, Coimbatore, Tamil Nadu – 641 018., IN
1 Department of Pharmacy Practice, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore, Tamil Nadu – 641402, IN
2 General Medicine, KG Hospital, Coimbatore, Tamil Nadu – 641 018., IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 14, No 2 (2022), Pagination: 72-74Abstract
Introduction: The prevalence of anaemia is high in developing countries due to poor economic, malnutrition, heredity diseases and pregnancy and reduced health care utilization. Increased Iron requirement and mal absorption of Iron also cause the Anaemia in chronic blood loss during menstrual periods. Methodology: A randomised, cross sectional study was conducted for 6 months Based on inclusion and exclusion criteria.120 anaemic patients were screened for biochemical tests. Results: Out of 120 patients, 32% were male and 68% were female. Majority of patients fall under the age group of 17 to 30 years. The educational status indicates, 40% were high school and 35% were illiterate. Majority of the patients were ideal body weight in 38% and 34% were under over weight. The severity was analysed based on Hb value and found that, 8% patient were severe, 8% were moderate and 88% were in mild anaemia. The mean Hb value was found that 10.82 mg/dl. Only 40% of patients are taking the daily breakfast regularly and 42% of female patients not consuming red meat, fish and chicken. Serum ferritin value is only 5.8 ng/ml, MCV found that 72.30 fL and Hb is 10.82 g/dl. Conclusion: The health education on healthy diet and creating awareness on risk factors of anaemia helps to avaoid the severity and complications of anaemia. The effective Pharmaceutical care services on anaemic patients are essential to prevent the morbidity and mortality rate.Keywords
Anaemia, Adolescent female, Menstrual cycle, Nutrition.References
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